hse—ha生理学系统是一系列应用广泛的完备产品，可用于整体动物生理学、立体或在体器官和组织灌注及组织浴槽研究。这些系统具有广泛的应用，包括传统的安全药理学、dmpk、毒理学、呼吸系统、心脏病学、分子生物学和生理学。每个系统都设计了标准的组件，再加一些其他配置以适合特殊研究的需要。。标注组件也意味着如果你是需要将现有设备配齐，或者进行系统升级，或者是完整的配套产品，你都只需要购买需要的构件。hse-ha生理学系统为你提供各种工具，使你的研究走向多产和成功。
我们提供大多数生理学检测设备，包括放大器、电极、传感器和电化学检测器。参数包括力、位移、压力、液体和气体流、心电图（单导联—12导联系统）、map（单个或多个部位）、脑电图、肌电图、连续支流灌注传统的血气参数和电解质的分析，可以选择程序化软件和传统的刺激器作为放大器、电极和传感器等产品的补充。
hse-daq系统产品家族（bdas、acad、haemodyn、isoheart、pulmodyn、pennock）可以记录你的初始信号，计算到处的参数，注释数据，快速简易的输入确定的数据用于分析。同时还可以选择用于进一步分析的软件模块，带状记录纸打印，自动和控制模块等。产品经过预先设置，打开包装即可使用，并专门设计符合你的系统配置和数据分析要求。
• optimized in-situ preparation
• negative-pressure ventilation to mimic more closely the invivo situation
• regular induction of hyperinflation of the lung (sigh, augmented breath)
• several perfusion modes using buffer solution or blood are available:
– constant flow perfusion
– constant pressure perfusion
– dual perfusion system(constant flow or constant pressure can be se-lected)
• continuous measurement of lung mechanics (tidal volume, resistance, compliance), and perfusate characteristics (pressure, flow, po2, pco2, ph)
• continuous measurement of lung weight (edema)
ventilation
the lung is placed in the artificial thoracic chamber and ventilated at negative pressure, it is connected via the tracheal cannula to the pneumotachometer for measurement of respiratory flow. the humidified ventilation medium (air or gas mixture) is constantly flowing past the distal end of the pneumotachometer.
perfusion
lungs can be perfused by either constant flow or constant pressure. although constant flow perfusion may mimic the in vivo situation more closely, it has the disadvantage that hydrostatic edema becomes inevitable during vasoconstriction. constant pressure perfusion permits higher perfusate flow rates since vasoconstriction decreases perfusate flow and hydrostatic edema is less likely to occur.
can be configured in one of three different perfusion modes:
1. constant flow perfusion
2. constant pressure perfusion
3. dual system to switch from constant flow to constant pressure and vice versa
lung weight changes
continuous measurement of weight changes of the lung is required for monitoring edema formation. this is possible during negative pressure ventilation inside the thoracic chamber by using the hse-edema balance ls 30 (weight transducer) (bs4 73-0593), range ±30 g, displacement 2 µm/gram. weight changes induced by raising or lowering the perfusion pressure can be used to assess vascular permeability by determining the filtration coefficient.
• optimized in-situ preparation
• negative-pressure ventilation to mimic more closely the invivo situation
• regular induction of hyperinflation of the lung (sigh, augmented breath)
• several perfusion modes using buffer solution or blood are available:
– constant flow perfusion
– constant pressure perfusion
– dual perfusion system(constant flow or constant pressure can be se-lected)
• continuous measurement of lung mechanics (tidal volume, resistance, compliance), and perfusate characteristics (pressure, flow, po2, pco2, ph)
• continuous measurement of lung weight (edema)
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