灌注系统概述

hse—ha生理学系统是一系列应用广泛的完备产品，可用于整体动物生理学、立体或在体器官和组织灌注及组织浴槽研究。这些系统具有广泛的应用，包括传统的安全药理学、dmpk、毒理学、呼吸系统、心脏病学、分子生物学和生理学。每个系统都设计了标准的组件，再加一些其他配置以适合特殊研究的需要。。标注组件也意味着如果你是需要将现有设备配齐，或者进行系统升级，或者是完整的配套产品，你都只需要购买需要的构件。hse-ha生理学系统为你提供各种工具，使你的研究走向多产和成功。

我们提供大多数生理学检测设备，包括放大器、电极、传感器和电化学检测器。参数包括力、位移、压力、液体和气体流、心电图（单导联—12导联系统）、map（单个或多个部位）、脑电图、肌电图、连续支流灌注传统的血气参数和电解质的分析，可以选择程序化软件和传统的刺激器作为放大器、电极和传感器等产品的补充。

hse-daq系统产品家族（bdas、acad、haemodyn、isoheart、pulmodyn、pennock）可以记录你的初始信号，计算到处的参数，注释数据，快速简易的输入确定的数据用于分析。同时还可以选择用于进一步分析的软件模块，带状记录纸打印，自动和控制模块等。产品经过预先设置，打开包装即可使用，并专门设计符合你的系统配置和数据分析要求。

the isolated heart size 5, ih-5, apparatus permits the use of hearts of small animals (rodents) as well as larger animals like rabbits. the flow limitation is about 500 ml/min. the perfusate is oxygenated in a 6 liter water jacketed reservoir with multiple ports for recirculation of the perfusate.

the system can be used for work in any one of three methods. the basic system is the retrograde perfusion mode (langendorff). by setting a defined threshold pressure at the flow resistance, the system works under constant pressure; by increasing the threshold pressure to a supermaximal pressure (300 mmhg) the system works under constant flow. a working heart system can be arranged by using the left atrium cannulating option. the complete system is mounted on a compact acrylic stand.

the system can also be used to simultaneously record all hemodynamic parameters as well as 8 ap-potentials and a 12-lead ecg. for this purpose, the ih-5 unit is additionally equipped with a circular holder for 8 map-electrodes and with an ecg multi-electrode in-sert in the heart chamber.

• high perfusion pressure (up to 300 mmhg); easy and fast changes of the perfusion pressure (within seconds)

• continuous measurement of heart mechanics (contractility, segment lengths), bioelectrical signals (ecg, map) and perfusate characteristics (pco2, po2, ph)

• the system can easily be modified to a working heart system, the special flow resistance and compliance chamber mimics closely the in-vivo afterload

• multiple monophasic action potentials (map) and simultaneous multilead ecg recording from isolated perfused rabbit heart

• extended system for hemodynamic and electrophysiology studies

• applications:– dispersion of ventricular repolarization